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How we create memories and why do some memories fade away?

Think back to a really vivid memory and notice how differently you recall it. Got it? Okay, now try to remember what you had for lunch three weeks ago. That second memory probably isn’t as strong, but  why not? This simple exercise shows how we create memories.

Why do we remember some things, and not others? And why do memories eventually fade? Let’s look at how memories form in the first place. When you experience something, like dialing a phone number, the experience is converted into a pulse of electrical energy that zips along a network of neurons.

How We Create Memories in the Brain

Information first lands in short-term memory, where it’s available from anywhere from a few seconds to a couple of minutes. It’s then transferred to long-term memory through areas such as the hippocampus, and finally to several regions across the brain. Neurons throughout the brain communicate at dedicated sites called synapses using specialized neurotransmitters.

Concept art showing two human silhouettes depicting how we create memories and how some memories fade over time.
An illustration showing how we create memories and how certain memories fade with time.

For a deeper overview of how memory operates in the brain and why it changes with age, review the guide on Harvard Health Publishing’s ‘Memory’ topic page.

If two neurons communicate repeatedly, a remarkable thing happens: the efficiency of communication between them increases. This process, called long-term potentiation, is considered to be a mechanism by which memories are stored long-term, but how do some memories get lost?

Why Some Memories Fade Over Time

Age is one factor. As we get older, synapses begin to falter and weaken, affecting how easily we can retrieve memories. Scientists have several theories about what’s behind this deterioration, from actual brain shrinkage, the hippocampus loses 5% of its neurons every decade for a total loss of 20% by the time you’re 80 years old to the drop in the production of neurotransmitters, like acetylcholine, which is vital to learning and memory. These changes seem to affect how people retrieve stored information. Age also affects memory-making abilities.

dive deeper into how nutrition supports memory and brain-function, see our article on Food and Brain Connection: How Diet Affects Your Mind.

Memories are encoded most strongly when we’re paying attention, when we’re deeply engaged, and when information is meaningful to us. Mental and physical health problems, which tend to increase as we age, interfere with our ability to pay attention, and thus act as memory thieves.

How Stress Weakens Memory Formation

Another leading cause of memory problems is chronic stress. When we’re constantly overloaded with work and personal responsibilities, our bodies are on hyperalert. This response has evolved from the physiological mechanism designed to make sure we can survive in a crisis. Stress chemicals help mobilize energy and increase alertness. However, with chronic stress our bodies become flooded with these chemicals, resulting in a loss of brain cells and an ability to form new ones, which affect our ability to retain new information.

In our increasingly connected world, staying focused means unplugging sometimes — see our article on The Benefits of Digital Detox: Why Digital Detox Is Essential in This Hyperconnected World for practical ways to reduce cognitive load.

Artistic silhouette with a glowing neural tree symbolizing how we create memories and strengthen brain connections.
A symbolic depiction of how we create memories through branching neural pathways.

How Depression and Isolation Damage Memory

Depression is another culprit. People who are depressed are 40% more likely to develop memory problems. Low levels of serotonin, a neurotransmitter connected to arousal, may make depressed individuals less attentive to new information. Dwelling on sad events in the past, another symptom of depression, makes it difficult to pay attention to the present, affecting the ability to store short-term memories. Isolation, which is tied to depression, is another memory thief. A study by the Harvard School of Public Health found that older people with high levels of social integration had a slower rate of memory decline over a six-year period.

How to Protect and Strengthen Your Memory

The exact reason remains unclear, but experts suspect that social interaction gives our brain a mental workout. Just like muscle strength, we have to use our brain or risk losing it. But don’t despair. There are several steps you can take to aid your brain in preserving your memories. Make sure you keep physically active. Increased blood flow to the brain is helpful. And eat well, your brain needs all the right nutrients to keep functioning correctly. And finally, give your brain a workout. Exposing your brain to challenges, like learning a new language, is one the best defenses for keeping your memories intact.

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